Jumat, 04 Oktober 2013

HEMOGLOBIN

HEMOGLOBIN merupakan cairan yang berwarna merah yang berada di dalam eritrosit.Apabila eritrosit dilisiskan, cairan ini keluar dan disebut hemolisat. Hemoglobin berfungsi untuk menangkap dan mengikat oksigen di paru-paru dan melepaskannya ke jaringan. Di jaringan hemoglobin berfungsi untuk menangkap dan mengikat karbondioksida dan melepaskannya di paru-paru. Hemoglobin memenuhi  seluruh eritrosit dan keberadaannya menentukan morfologi maupun kelenturan eritrosit.

STRUKTUR HEMOGLOBIN


  • Berat molekul 68 kilo Dalton
  • Tiap molekul Hb terdiri dari empat gugus Hem dan satu gugus Globin 
  • Satu gugus Globin terdiri dari dua pasang rantai polipeptida. Rantai polipeptida merupakan rangkaian asam amino.
RANTAI POLIPEPTIDA
Rantai Polipeptida terdiri dari :  

  •  Rantai  alfa
  •  Rantai beta
  •  Rantai gamma
  •  Rantai  delta
  •  Plus 2 rantai lainnya
KELAINAN HEMOGLOBIN

  1. Substitusi asam amino pada rantai polipeptida diganti asam amino lain
  2. Gangguan produksi  satu atau lebih rantai polipeptida
  3. Hb F persisten
  4. Kelainan genetik
BERBAGAI CONTOH KELAINAN HEM :

  • Acute intermittent porphyria
  • Congenital erythropoietic porphyria
  • Porphyria cutanea tarda
  • Hereditary copro porphyria
  • Variegate porphyria
  • Erythropoietic protoporphyria
  • Anemia sideroblastik

1 komentar:

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    For those people who are lupus sufferers and maybe reading this, I find it hard that people are still ignorant when it comes to LUPUS and have no idea what the illness is all about and still flippant about it even in the medical world.
    After my daughter collapsed at home she was seen by one of the Consultants in the Lupus Unit who performed more tests and confirmed that she was negative with the Anti-RO antibodies. when I was told this, as I was slowly thinking I was losing my marbles and this was all in my head.
    The Doctor prescribed a course of treatment but said that it would take about 8-9 months for the drugs to start working. I felt relieved to think that there was light at the end of the tunnel but still quite daunted by her having to cope with feeling the way. After 2months of taking the medication the symptoms seemed to get worse, She had fevers, cold sweats, chest pains, constantly nauseous and she was finding it difficult to breathe. Her Doctor thought that the difficulty breathing may have been caused by one of the anti-inflammatory drugs and stopped them straight away.

    But Everything started to get easier from the point we came across Dr Itua Herbal Medicine through (www.drituaherbalcenter.com). When I first contacted Dr Itua Herbal Center through his email : drituaherbalcenter@gmail.com. He told us that the drugs they'd used had aggravated the Lupus and caused it to flare more badly. The miraculous new treatment (Herbal Medicine) was for her to start the medicine sooner which was my thoughts, which of course was helpful.
    His medicine is very effective, she experienced no symptoms for the past 3year. If you/your relatives have the same problem, do not expose yourself to more danger, use a herbal remedy that is safe and effective. Contact Dr Itua directly for any type of disease.

    BalasHapus